Endocrine Abstracts

Alternative treatments for thyroid disorders include animal thyroid extract and preparations containing iodine. These treatments can affect thyroid status and their use may be unrecognised by doctors treating patients with thyroid disorders. We aimed to determine the nature, availability and use of alternative treatments for thyroid disorders (ATTDs).Patient questionnaires were administered to all patients with a diagnosis of a thyroid disorder attending...

In the pathogenesis of obesity, dysregulated tissue cortisol metabolism (controlled by 11β-HSD1), is postulated to be involved. Fifteen patients (seven mens, mean BMI 50.8±7 kg/m2) awaiting Roux En Y gastric Bypass (RYGB) surgery underwent assessment of 11β-HSD1 activity using cortisol generation profile. Corticosteroids in serum and subcutaneous adipose tissue microdialysis fluid and urinary corticosteroid metabolites were analysed by liquid and gas ...